About this trial
In order to optimize sports performance, high-level athletes are required to manage conflicting training objectives, which often result in periods of high-volume training. These athletes need to perform heavy resistance training sessions to promote physiological adaptations, which consequently induce fatigue. Yet, they need to minimize fatigue to perform subsequent high-quality training sessions often within the same day. To support these training endeavours, a high-quality dietary regimen and adequate protein consumption is deemed to be an essential component of an athlete's recovery plan, as it has been shown to support muscle recovery and reduce muscle inflammation following exercise. Indeed, current sports nutrition recommendations advocate for the consumption of dietary protein and carbohydrate after exercise to promote tissue repair and replenish muscle energy stores (glycogen). Additionally, previous research has shown how water immersion therapies post-exercise may alleviate fatigue and restore performance. However, little is known about how different temperatures, as well as timing of cold-water immersion can support performance recovery in a population of athletes adhering to contemporary post-exercise nutrition recommendations. The objective of this project is to investigate the effects of timing of cold-water immersion relative to exercise on performance recovery within the same day, as well as to investigate whether cold water immersion augments blood amino acid concentrations after exercise and protein intake.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Healthy adult between 18 - 40 years (inclusive).
Individual with a BMI between >18.5 and <30 kg/m2 (inclusive).
Individual who is in good general health (no uncontrolled diseases or conditions).
individual with a history of regular resistance training ≥2 per week for the past six-months.
Disqualifiers
Individual who is lactating, pregnant or planning to become pregnant during the study.
Females with irregular menstrual cycles (defined as outside 24-38 days cycle range, based on self-reports).
Individual who adheres to a diet (e.g., vegan diet) that restricts consumption of dairy products.
Has a known sensitivity, intolerability, or allergy to any of the study products or their excipients (i.e., lactose intolerant).
Trial design
Crossover
Treatments tested in this trial
immediate cold-water immersion
Other interventionimmediate 10 minute water immersion in 10 degree Celsius
delayed cold-water immersion
Other intervention3 hour delayed 10 minute water immersion in 10 degree Celsius
immediate thermoneutral water immersion
Other interventionimmediate 10 minute water immersion in 35 degree Celsius
Treatment groups
Trial outcomes
Primary outcomes
Prolonged maximum voluntary isometric contraction of the knee extensors peak force
The participant will be asked to perform one five-second maximum voluntary isometric contraction of the knee extensors on an isometric dynamometer at a 60° angle of the knee joint. The force-time profile will be used to derive the peak force (Newton)
Secondary outcomes
postprandial plasma total amino acid concentration incremental area-under-the-curve
Free leucine, isoleucine, valine, histidine, lysine, methionine, phenylalanine, threonine, tryptophan, arginine, glutamine, glycine, alanine, serine, glutamic acid, aspartic acid, asparagine, tyrosine, cysteine, proline (combined) at 11 timepoints (time = -120, 0, 15, 30, 45, 60, 90, 120, 180, 240, 300 minutes) umol/L
postprandial plasma branched chain amino acid concentration incremental area-under-the-curve
Free leucine, isoleucine, valine (combined) at 11 timepoints (time = -120, 0, 15, 30, 45, 60, 90, 120, 180, 240, 300 minutes) umol/L
postprandial plasma essential amino acid concentration incremental area-under-the-curve
Free leucine, isoleucine, valine, histidine, lysine, methionine, phenylalanine, threonine, tryptophan (combined) at 11 timepoints (time = -120, 0, 15, 30, 45, 60, 90, 120, 180, 240, 300 minutes) umol/L
postprandial plasma leucine concentration incremental area-under-the-curve
leucine at 11 timepoints (time = -120, 0, 15, 30, 45, 60, 90, 120, 180, 240, 300 minutes) umol/L
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