The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of California, Davis

About this trial

The purpose is to conduct a dietary intervention study in which human participants will consume beverages sweetened with erythritol or aspartame, each for 2 weeks, in a randomized crossover design

Eligibility criteria

Qualifiers

BMI ≥ 27 kg/m2

Disqualifiers

• History of blood clot, transient ischemic attack (TIA), stroke, angina, heart attack, or peripheral vascular disease, or current cancer diagnosis.

Pregnant or lactating women

Current, prior (within 12 months), or anticipated use of medications for treatment of hyperlipidemia, high blood pressure or diabetes, or any medication that in the opinion of the investigators will confound results.

Unwilling to forego the use of anti-inflammatory medication during study.

Trial design

Treatments tested in this trial

  • Erythritol
  • Aspartame

Treatment groups

24 Participants
are divided into 2 treatment groups