The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
ConditionCardiovascular Diseases
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-60
SponsorPenn State University
About this trial
This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.
Eligibility criteria
Qualifiers
LDL-C ≥100 mg/dL and ≤190 mg/dL
BMI of 25-40 kg/m2
Blood pressure <140/90 mmHg
Fasting blood glucose <126 mg/dL
Disqualifiers
Type 1 or type 2 diabetes or fasting blood glucose ≥126 mg/dL
Prescription of anti-hypertensive, lipid lowering or glucose lowering drugs
Intake of supplements that affect the outcomes of interest and unwilling to cease during the study period
Diagnosed liver, kidney, or autoimmune disease
Trial design
Treatments tested in this trial
- Healthy Dietary Pattern with Cottonseed Oil
- Healthy Dietary Pattern with Fatty Acid-Matched Plant Oils
- Healthy Dietary Pattern with PUFA:SFA Ratio-Matched Plant Oil
Treatment groups
52 Participants
are divided into 3 treatment groupsSponsors and collaborators
Penn State University
Lead sponsor
Cotton Incorporated
Collaborator
Source ClinicalTrials.gov