The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-41
SponsorUniversity of Reading
About this trial
This clinical trial investigates the effects of Vitamin B6 supplementation on neural inhibition using electroencephalography (EEG), in relation to depression and anxiety symptoms in participants from the general population with a relatively high level of symptoms at baseline. Researchers will compare a placebo group to high-dose Vitamin B6 to test the hypothesis that Vitamin B6 moves the excitation/inhibition balance towards inhibition.
Eligibility criteria
Qualifiers
Over 18 years of age and under 41
Mild to moderate anxiety and/or depression
Normal or corrected to normal vision
Disqualifiers
not taking daily dietary supplement containing >2 mg Vitamin B6
not taking medication that is a GABA agaonist (our team will check this with you)
not be pregnant
no medical history of epilepsy
Trial design
Treatments tested in this trial
- Pyridoxal-5'-Phosphate supplement
- Placebo Supplementation
Treatment groups
44 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Reading
Lead sponsor
eBeauty Ltd Innopure, Regus House, Cardiff Gate Business Park, Malthouse Avenue, Cardiff, CF23 8RU
Collaborator
Source ClinicalTrials.gov