The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorZiekenhuis Oost-Limburg

About this trial

Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures. Many factors influence the onset and duration of peripheral nerve blocks. In the advent of ultrasound-guided nerve blocks, the accuracy in administering LA has significantly improved, potentially reducing the required dosage, which is also associated with less risk for toxicity. However, the effect of the concentration of LA on the onset time and duration of ultrasound-guided ankle blocks for forefoot surgery has not yet been studied. This poses a clinically relevant dilemma regarding the necessity of administering lower or higher concentrations of ropivacaine to achieve a clinically relevant faster onset time and longer duration of an ankle block.

Eligibility criteria

Qualifiers

Provide signed and dated informed consent

Age 18 up to and including 75 years, scheduled for elective forefoot surgery for hallux valgus repair, with or without one or more of the following: minor toe procedures, osteotomies, arthrodesis or toe extensor/flexor procedures, under unilateral ankle block at ZOL Genk

ASA physical I-II-III

Able to ambulate (ability to walk independently, with or without assistive devices)

Disqualifiers

Language barrier

Preexisting lower extremity neuropathy

Contraindications to ankle block (local infection, edema, burn, soft tissue trauma, or distorted anatomy with scarring in the area of block placement)

Contraindications for use of NSAIDs

Trial design

Treatments tested in this trial

  • 0.25% ropivacaine
  • 0.5% ropivacaine
  • 1% ropivacaine

Treatment groups

174 Participants
are divided into 3 treatment groups

Sponsors and collaborators