The Effects of Vitamin C on Acute-Exercise in Postmenopausal Females
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45+
SponsorUniversity of Virginia
About this trial
This study is looking at whether vitamin C can help improve oxidative stress and blood vessel health in females after menopause. We will see if taking different amounts of vitamin C for a few days changes how the body handles stress from exercise. This could lead to safer ways to protect females from heart disease without using hormone therapy.
Eligibility criteria
Qualifiers
Post-menopausal (for females; defined as no menstrual cycle for 1-year)
Sedentary (<150min of moderate-intensity exercise per week or not engaged in a regular exercise program)
Non-smoking
Weight stable (+/-3 kg over the past 3 months)
Disqualifiers
Overt CVD
Any condition or medication contraindicating safe exercise
Hormone replacement therapy (last 3-months)
Use of vasoactive medications (e.g., calcium channel blockers, statins, ACE inhibitors, ARBs, nitrates, alpha-/beta-blockers, diuretics), diabetes, or unstable medication regimens
Trial design
Treatments tested in this trial
- Vitamin C (Ascorbic Acid)
Treatment groups
30 Participants
are divided into 4 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov