The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorBeijing Tiantan Hospital
About this trial
This study assesses the efficacy and safety of endovascular therapy in patients with acute basilar artery occlusion with large core infarction within a multicenter, prospective, open-label, blinded endpoint, randomized controlled trial
Eligibility criteria
Qualifiers
The age ranged from 18 to 80 years
Acute ischemic stroke in posterior circulation, the time from stroke onset (or finally found normal) to randomization was within 24 hours
Acute basilar artery occlusion confirmed by CTA,MRA,or DSA
Posterior circulation large core infarction:NCCT or DWI showed pc-ASPECTS≤5, or Pons-Midbrain Index (PMI)≥3
Disqualifiers
Any sign of intracranial hemorrhage (except microbleeds) on brain imaging prior to randomization
Complete cerebellar infarct with significant mass effect, or bilateral thalamic infarction as evidenced by baseline neuroimaging
Known or highly suspected chronic occlusion of basilar artery
History of contraindication for contrast medium (except mild rash)
Trial design
Treatments tested in this trial
- Endovascular Recanalization Strategy
- Best Medical Management
Treatment groups
308 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov