The EnvScore-Aorte Diagnostic Study Protocol for the Identification of Acute Aortic Syndrome

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Besancon

About this trial

The goal of this retrospective observational study is to evaluate the diagnostic performance of the AORTAs score integrated with environmental exposure data (AORTAs-E) for the identification of Acute Aortic Syndrome (AAS) during initial maangement in the emergency departement.

The main question it aims to answer is:

Can the integration of real-time meteorological and atmospheric pollution data improve the early identification of AAS in patients presenting in the emergency department for chest, abdominal, or back pain?

Researchers will analyze medical records and environmental data for 580 adult patients (290 cases with confirmed AAS and 290 controls) managed at the University Hospital of Besançon between 2014 and 2026. Environmental exposure, including temperature and pollutant concentrations, will be calculated based on each patient's residential address to determine if adding these factors to clinical data increases diagnostic accuracy.

Eligibility criteria

Qualifiers

Adults (>18 years)

Diagnosis of AAS (aortic dissection, intramural hematoma, or penetrating atherosclerotic ulcer) identified according to medicalization programs for information systems

Diagnosis confirmed by imaging (CTA, TTE, or TOE)

Adults (>18 years)

Disqualifiers

Post-traumatic or iatrogenic AAS.

Subacute (8-30 days) or chronic symptoms (>30 days).

Patients under legal protection or unable to provide consent/non-opposition.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

580 Participants
are grouped into 2 trial groups

Locations

This trial has no locations