About this trial
This research study wants to learn about Chronic Kidney Disease (CKD) with Obesity, and Heart Failure with preserved Ejection Fraction (HFpEF) and better ways to evaluate these diseases. HFpEF means that the heart is not able to fill properly with blood while it is resting so the amount of blood pumped out to the body is less than it would be if it was filling properly. The study is being done to describe the differences in how the kidneys handle protein and salt in participants with HFpEF and obesity compared to healthy persons.
Eligibility criteria
Qualifiers
Adults 18-75 years old
Normal kidney function
No heart failure
BMI 25-30kg/m2
Disqualifiers
Diagnosis of chronic illness
eGFR<60mL/min/1.73m2
Pregnancy or breast feeding
History of cutaneous or allergic reaction to iodine-based products of contrast dyes
Trial design
Treatments tested in this trial
- High protein and sodium meal