The GEOLynch Cohort Study
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorWageningen University
About this trial
The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.
Eligibility criteria
Qualifiers
Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene.
Aged between 18 and 80 years at inclusion.
Disqualifiers
Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP)
(Chronic) Inflammatory bowel disease
Non-Dutch speaking
Dementia or another mental condition that makes it impossible to fill out questionnaires
Trial design
Treatments tested in this trial
- No intervention, observational study.
Treatment groups
1,000 Participants
are divided into 1 treatment groupSponsors and collaborators
Wageningen University
Lead sponsor
Wereld Kanker Onderzoek Fonds
Collaborator
Dutch Cancer Society
Collaborator
Funding: Biobanking and BioMolecular resources Research Infrastructure The Netherlands
Collaborator
Source ClinicalTrials.gov