The German National CRS Registry (GenreCRS): Clinical Evaluation of the New European Academy for Allergy and Clinical Immunology (EAACI) Criteria for CRSwNP Disease Control, Remission and Cure in a Real-World Evidence Study Approach

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12+
SponsorÄrzteverband Deutscher Allergologen e.V.

About this trial

The objective of the study is to establish a registry of patients diagnosed with Chronic Rhinosinusitis with and without Nasal Polyps (CRSwNP/CRSsNP) to collect comprehensive longitudinal real-world evidence from specialised treatment centres in Germany. The primary analysis will concentrate on the treatment efficacy and safety of biologic drugs with a focus on defining disease Control, Remission, and Cure as well as to validate the corresponding clinical evaluation criteria.

Eligibility criteria

Qualifiers

Patients above the age of 12 years

Patients who are diagnosed with CRS according to internationally valid guidelines (EPOS 2020)

Patients who provide written informed consent or by a legal representative

Disqualifiers

Patients below the age of 12 years at initiation

Patients who do not provide written consent or withdraw their consent

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

500 Participants
are grouped into 3 trial groups

Locations

This trial has no locations

Sponsors and collaborators

Ärzteverband Deutscher Allergologen e.V.

Lead sponsor

German Society of Otorhinolaryngology, Head and Neck Surgery

Collaborator