About this trial
The i4i PRODICT® study has been developed to investigate the uptake and acceptability of the i4i PRODICT® test which combines both common and rare genetic changes (genetic variants) into one saliva-based DNA test to estimate a person's future risk of prostate cancer (PrCa) in people of varying ethnicities.
Eligibility criteria
Qualifiers
People with a prostate* (PwP). *People with a prostate is defined as people born male.
Aged 40 to 55 years.
People of either (i) Black African/Black African-Caribbean; (ii) White European; or (iii) South Asian or East Asian ancestry. These are defined as individuals with 4 grandparents of the same ancestry.
Absence of any psychological, familial, sociological or geographical situation potentially hampering compliance with the study protocol and follow-up schedule.
Disqualifiers
Previous diagnosis of prostate cancer.
People of mixed ancestry
Previous diagnosis of cancer with a life-expectancy of less than five years.
Negative prostate biopsy within one year before recruitment.
Trial design
Treatments tested in this trial
- The i4i PRODICT® test.
- Prostate cancer screening
- MRI Scan
- Prostate Biopsy
Treatment groups
Sponsors and collaborators
Institute of Cancer Research, United Kingdom
Lead sponsor
Royal Marsden NHS Foundation Trust
Collaborator
Imperial College London
Collaborator