The Impact of LBBAP vs RVP on the Incidence of New-onset Atrial Fibrillation in Patients With Atrioventricular Block

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorPeking Union Medical College Hospital

About this trial

This is a single-center, randomized controlled study. The aim of this study is to compare the impact of left bundle branch area pacing versus traditional right ventricular pacing on the incidence of atrial fibrillation in patients with atrioventricular block.

Eligibility criteria

Qualifiers

Adult patients aged 18-85;

AV block patients with ventricular pacing indications and the expected rate of ventricular pacing(VP)> 40%, including (a) third-degree AV block; (b) second degree AV block (type II); (c) intermittent advanced AV block with expected VP>40%; (d) symptomatic first degree AV block and PR interval on ECG > 300ms;

Signed informed consent;

Disqualifiers

Baseline echocardiographic assessment of patients with impaired LV function (LVEF<50%);

Patients with the history of atrial fibrillation;

Having difficulties in follow-up: Those who cannot accept 2-year follow-up on time due to physical condition or other reasons;

Pacemaker replacement without new implanted ventricular electrodes;

Trial design

Treatments tested in this trial

  • left bundle branch area pacing
  • right ventricular pacing

Treatment groups

530 Participants
are divided into 2 treatment groups