The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorThe First Affiliated Hospital of Soochow University
About this trial
This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth. The research is a prospective, randomized controlled trial involving 424 participants from two hospitals. The primary objective is to investigate the impact of local anesthetic solution temperature on intrapartum fever in parturients. Secondary goals include assessing the impact on the efficacy of epidural analgesia and various maternal and neonatal outcomes. Participants will receive either 37°C or 23°C anesthetic solutions, and data will be collected on fever rates, pain scores, and other health indicators. The study runs from January 2024 to December 2026.
Eligibility criteria
Qualifiers
Requesting epidural analgesia;
Aged 18 or older;
At least 37 weeks of gestation;
Those delivering vaginally.
Disqualifiers
Contraindications to epidural analgesia;
Pre-existing fever (≥38°C) before labor;
Use of NSAIDs or other types of antipyretics before labor;
Multiple pregnancy (carrying more than one fetus);
Trial design
Treatments tested in this trial
- In the context of epidural analgesia, the temperature of the local anesthetic solution is elevated to 37°C utilizing a blood transfusion and infusion warmer.
Treatment groups
424 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov