The Impact of Melatonin Lotion on Sleep and Mental Health

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-21
SponsorUniversity of Redlands

About this trial

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.

Eligibility criteria

Qualifiers

a T score ≥ 48 on the sleep disturbance short form Patient-Reported Outcomes Measurement Information System (PROMIS) measure, and

a T score ≥ 55 on the anxiety or depression short form PROMIS measures (mild symptoms or more)

Disqualifiers

currently using antidepressant, anti-anxiety, or sleep medication including melatonin

are pregnant

have allergies/sensitivities to scented lotion

are unwilling to commit to keeping a similar bedtime (± 1 hour) during treatment weeks.

Trial design

Treatments tested in this trial

  • Melatonin lotion
  • Placebo lotion

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators