The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorKonya City Hospital

About this trial

This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.

Eligibility criteria

Qualifiers

Adult patients aged 40 years and older

Undergoing elective cardiac surgery (e.g., isolated CABG, isolated valve surgery, or combined CABG+valve surgery via sternotomy)

Regular use of at least one antihypertensive medication for at least 4 weeks prior to the operation date

Voluntary participation and signed informed consent

Disqualifiers

Emergency surgery

Preoperative shock or requirement for high-dose inotropic/vasopressor therapy

End-stage liver or kidney failure

Uncontrolled hypertension

Trial design

Treatments tested in this trial

  • Chronic Antihypertensive Medication Use

Treatment groups

160 Participants
are divided into 1 treatment group

Sponsors and collaborators