The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital
About this trial
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral nutrition.
Eligibility criteria
Qualifiers
Adult male or non-pregnant female volunteers (age 18+)
Scheduled for a cardiac surgical procedure with planned post-operative admission to the ICU for >48 hours
Able and willing to give consent and comply with study procedures
Disqualifiers
Blind, deaf or unable to speak English
Women who are pregnant or nursing
Contraindications to safe use enteral nutrition, including gastrointestinal obstruction
Personal history of intestinal malabsorption, gallbladder disease or pancreatitis
Trial design
Treatments tested in this trial
- Time-of-day of enteral nutrition provision (daytime first)
- Time-of-day of enteral nutrition provision (nighttime first)
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov