The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age19-29
SponsorUniversity School of Physical Education, Krakow, Poland

About this trial

* Cognitive assessment of the influence of a 4-week proprietary training program under normobaric hypoxia conditions on the levels of inflammatory markers, disturbances in prooxidant-antioxidant balance, degree of intestinal damage, and mitochondrial energy production rate in young sedentary males. * Applied objective: Development of practical training guidelines utilizing training in normobaric hypoxia conditions to enhance mechanisms related to oxygen transport, adaptive changes within the immune system, body's antioxidant capacity, gut permeability, substrate utilization efficiency, and mitochondrial function for coaches and athletes.

Eligibility criteria

Qualifiers

no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required.

Disqualifiers

changes in diet during the experiment, smoking and abuse of alcohol and/or other stimulants.

Trial design

Treatments tested in this trial

  • Exercise and environmental conditions

Treatment groups

50 Participants
are divided into 4 treatment groups

Sponsors and collaborators

University School of Physical Education, Krakow, Poland

Lead sponsor

Ministry of Education and Science,Poland

Collaborator