The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDana-Farber Cancer Institute

About this trial

The purpose of this study is to determine the feasibility of a prehabilitation program for participants diagnosed with rectal cancer undergoing neoadjuvant chemotherapy and/or radiation, followed by surgical resection.

The names of the groups in this research study are:

* Group A: Prehabilitation program * Group B: Usual Care

Eligibility criteria

Qualifiers

Age greater than or equal to 18 years at time of enrollment.

English-Speaking.

Diagnosis of clinical stage II-III rectal cancer.

Planned, ongoing or just completed neoadjuvant treatment, including either 1) chemoradiation, 2) total neoadjuvant therapy (TNT), or 3) chemotherapy only; and anticipated surgical resection to follow.

Disqualifiers

Distant metastatic disease known at the time of diagnosis.

Functional incapacity (i.e., incapable of performing exercise testing).

Comorbid conditions or cognitive/physical impairments that contraindicate exercise.

Currently undergoing treatment for a secondary primary tumor, in addition to primary rectal cancer.

Trial design

Treatments tested in this trial

  • Prehabilitation Program

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators