The Impact of Probiotics on Sperm Quality in Middle-aged Men
ConditionSperm Quality
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age40-59
SponsorWecare Probiotics Co., Ltd.
About this trial
The clinical trial aims to investigate the impact of probiotic strain BL21 on sperm quality among 46 middle-aged male participants. The primary objective is to validate whether probiotic strain BL21 can effectively improve sperm quality among middle-aged male participants. Initially, participants were instructed to consume the recommended amount of probiotic powder for approximately 8 weeks. At baseline, week 4, and week 8 endpoints, semen analysis, hormone level testing, serum cytokine testing were conducted on the participants, and stool samples were collected from them.
Eligibility criteria
Qualifiers
Subjects aged 40-59 years old.
Normal levels of gonadotropins, testosterone, and serum prolactin.
No use of other traditional Chinese and Western medicines for oligoasthenoteratozoospermia treatment in the past 3 months.
Patients who can understand the clinical study and commit to complying with the study requirements and procedures.
Disqualifiers
Organic lesions of the reproductive system;
Use of antibiotics in the two weeks prior to recruitment;
Sexual dysfunctions such as erectile dysfunction, ejaculatory abnormalities, preventing completion of sexual intercourse;
Genitourinary infections, such as Chlamydia or Mycoplasma infections;
Trial design
Treatments tested in this trial
- probiotic product
- Maltodextrin
Treatment groups
46 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov