The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorItshak Amsalem
About this trial
The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure.
The main questions it aims to answer are:
Does sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity?
Participants admitted to the hospital with heart failure and fluid overload will take part in this study.
Participants will:
Use a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care
Researchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.
Eligibility criteria
Qualifiers
Adults aged 18 years or older
Hospitalized with decompensated heart failure and clinical evidence of fluid overload
Diagnosis of heart failure (reduced or preserved ejection fraction)
Clinically indicated for diuretic therapy
Disqualifiers
Known central sleep apnea as the predominant sleep-disordered breathing type
Current treatment with continuous positive airway pressure (CPAP)
Acute respiratory failure requiring mechanical ventilation
Conditions preventing proper use of the WatchPAT device (e.g., severe hand or finger injury)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
50 Participants
are grouped into 1 trial groupSponsors and collaborators
Itshak Amsalem
Lead sponsor
Shaare Zedek Medical Center
Sponsor institution
Source ClinicalTrials.gov