The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorStanford University

About this trial

The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and UC are very limited. Fasting mimicking diets (FMD) have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after three cycles of a five-day period of the fasting mimicking diet, and may provide rationale for its use to treat UC.

Eligibility criteria

Qualifiers

Mild to moderate Ulcerative Colitis on the partial Mayo Score out of 9 (score between 2 to 7)

Age of 18-70 at start of study (inclusive)

Disqualifiers

Women who are pregnant or nursing or expect to be pregnant

Individuals allergic to nuts

Individuals with a body mass index (BMI) lower than 18

Individuals diagnosed with a serious medical condition as defined by the patient's physician, unless approved in writing by a physician

Trial design

Treatments tested in this trial

  • Fasting Mimicking Diet
  • Regular Diet

Treatment groups

75 Participants
are divided into 2 treatment groups

Sponsors and collaborators