About this trial
The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and UC are very limited. Fasting mimicking diets (FMD) have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after three cycles of a five-day period of the fasting mimicking diet, and may provide rationale for its use to treat UC.
Eligibility criteria
Qualifiers
Mild to moderate Ulcerative Colitis on the partial Mayo Score out of 9 (score between 2 to 7)
Age of 18-70 at start of study (inclusive)
Disqualifiers
Women who are pregnant or nursing or expect to be pregnant
Individuals allergic to nuts
Individuals with a body mass index (BMI) lower than 18
Individuals diagnosed with a serious medical condition as defined by the patient's physician, unless approved in writing by a physician
Trial design
Treatments tested in this trial
- Fasting Mimicking Diet
- Regular Diet