The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

ConditionsGastrointestinal Complication Intestinal Obstruction Gastroschisis Hirschsprung Disease Omphalocele Midgut Volvulus

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age0-55

SponsorSeattle Children's Hospital

About this trial

This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.

Eligibility criteria

Qualifiers

Infants with gastroschisis, giant omphalocele, intestinal atresia, mid-gut volvulus, hirschsprungs disease.

Disqualifiers

Infant has already been on feeds

Infants <34 weeks gestation

Parents with contraindications to providing milk (i.e. drug use-cocaine, fentanyl, meth BUT oxy/suboxone/marijuana OK)

Complicated gastroschisis

Trial design

Treatments tested in this trial

Standard of Care
Exclusive Human Milk

Treatment groups

116 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Seattle Children's Hospital

Lead sponsor

Source ClinicalTrials.gov