This study aims to assess the influence of specialized products based on ice cream on esophageal motility
willingness to participate based on signed written informed consent;
no qualitative changes in treatment within 6 months before enrollment (i.e., the introduction of a new antidiabetic therapy);
doses of anti-diabetic medications should be stable for 6 month in patients who receive metformin, gliptins, sulfonylureas, sodium/glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 agonists (GLP-1) or insulin.
no new medications during participation in the study
Pregnancy and breastfeeding;
Liver cirrhosis based on liver histology, or liver stiffness measurement (LSM > or = 14 kPa by Fibroscan), or APRI > or= 1; or BARD score > or = 2.
Diarrhea of any type (watery stool more than 3 times a day).
Chronic heart failure (I-IV class by NYHA).
Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology
Lead sponsor
Russian Science Foundation
Collaborator
Group of companies EFKO
Collaborator