The Intensive Nutritional Support in Esophageal Cancer Undergoing Neoadjuvant Therapy
ConditionEsophageal Cancer
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSichuan University
About this trial
Patients with esophageal cancer undergoing neoadjuvant therapy were selected as research subjects for nutritional risk screening and malnutrition assessment. Patients identified with nutritional risk were randomized into the standard nutrition therapy group (SNT) and the intensive nutrition therapy group (INT). The surgical rate was evaluated in both groups of patients, and the effects of nutritional support therapy on nutritional status and quality of life were investigated.
Eligibility criteria
Qualifiers
Esophageal cancer；
Patients were staged as cT1b-cT2N+M0 or cT3-cT4a, any N, M0. Based on the location of the tumor and clinical staging, they were defined as locally advanced resectable esophageal cancer；
Patients planned for neoadjuvant therapy, with radical surgical resection intended after neoadjuvant treatment；
Normal gastrointestinal function；
Disqualifiers
Other tumors, including pancreatic cancer, liver cancer and other solid digestive tract tumors, colon cancer, rectal cancer and other tubular lower digestive tract tumors;
Have serious heart, lung and brain diseases;
Patients with unstable vital signs and multiple organ failure;
The patient has poor cognitive ability and is unable to answer questions or fill out questionnaires;
Trial design
Treatments tested in this trial
- Enteral Nutrition
Treatment groups
200 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov