About this trial
This study aims to determine the mechanisms via which krill oil supplementation increases muscle strength and whether this translates to improvements in gait and functional characteristics in older adults. The studies we will carry out will establish, in healthy older adults, the effects of 6 months of supplementation with krill oil
Objective 1) Muscle structure and function Hypothesis: Krill oil supplementation will increase muscle size and strength alongside positive changes in muscle architecture (pennation angle and fascicle length).
Objective 2) Neuromuscular control and central nervous system (CNS) function Hypothesis: Krill oil supplementation will improve Neuromuscular Junction (NMJ) transmission stability and increase central drive and intramuscular coherence, as a measure of muscle synergy.
Objective 3) Gait and functional characteristics Hypothesis: Krill oil supplementation will improve gait and functional characteristics.
Eligibility criteria
Qualifiers
body mass index (BMI) </= 30 kg/m2
Age >/= 65 years
Capacity to consent
Living within the Glasgow area
Disqualifiers
Diabetes mellitus
Severe cardiovascular disease
Seizure disorders
Uncontrolled hypertension (>150/90mmHg)
Trial design
Treatments tested in this trial
- Vegetable oil
- Krill oil