The Link Between Physical Activity and Brain Health in Healthy Adults

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-75
SponsorTechnical University of Madrid

About this trial

The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is:

Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.

Eligibility criteria

Qualifiers

Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days/week of moderate-vigorous intensity).

Group B: sedentary individuals, (i.e., perform <150 min of moderate intensity exercise per week or IPAQ score<600 MET min/week).

In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations.

Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition

Disqualifiers

Medical conditions that have a high risk of associated cognitive symptoms.

Severe head injury with loss of consciousness within the previous 5 years.

Alcoholism (>3 alcoholic drinks per day).

Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

60 Participants
are grouped into 2 trial groups

Sponsors and collaborators