About this trial
The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is:
Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.
Eligibility criteria
Qualifiers
Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days/week of moderate-vigorous intensity).
Group B: sedentary individuals, (i.e., perform <150 min of moderate intensity exercise per week or IPAQ score<600 MET min/week).
In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations.
Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition
Disqualifiers
Medical conditions that have a high risk of associated cognitive symptoms.
Severe head injury with loss of consciousness within the previous 5 years.
Alcoholism (>3 alcoholic drinks per day).
Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics.
Trial design
Treatments tested in this trial
- Not listed