The Liver Care Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-110
SponsorZealand University Hospital

About this trial

The goal of this clinical trial is to evaluate the efficacy of screening for liver disease with liver stiffness measurement on abstinence or light consumption after 6 months in individuals who are receiving treatment for alcohol use disorder and without a history of liver disease. The investigators will conduct a randomized controlled trial with concealed allocation comparing A) an invitation to a liver stiffness measurement, blood sampling and leaflet on alcohol-related disease (intervention) with B) an invitation to blood sampling (control). The primary outcome is 'abstinence or light consumption' (≤ 10 units/week) throughout the last months, and assessed 6 months after randomization.

Eligibility criteria

Qualifiers

Attending outpatient treatment for alcohol use disorder (international classification of disease version 10: F102: alcohol dependence or F101: harmful alcohol use) at Novavi Køge or Novavi Roskilde

Informed written consent

Disqualifiers

Not speaking Danish or English

Severe liver disease (known by the participant)

Trial design

Treatments tested in this trial

  • Transient Elastography

Treatment groups

408 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Zealand University Hospital

Lead sponsor

Novavi

Collaborator

Aarhus University Hospital

Collaborator

Frederiksberg University Hospital

Collaborator

University of Copenhagen

Collaborator