The MAI-FOIE Cohort
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age10+
SponsorNantes University Hospital
About this trial
The MAI-FOIE cohort will be a French multicenter cohort with the development of a biobank including patients with autoimmune, metabolic and medicated liver diseases
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
age≥10 years old
weight≥25kg
ALT>2N or IgG>1.1N
Presence of autoantibodies : ANA (antinuclear), ML (anti-smooth muscle), SLA (anti-soluble liver antigen), LKM1 (anti-endoplasmic reticulum), LC1 (anti-liver cytosol)
Disqualifiers
None
Trial population
Patients from 10 years old to patients without limit age, male or female, with Auto-Immune Hepatitis or Metabolic steatohepatitis or Drug induced Hepatitis
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
800 Participants
are grouped into 2 trial groupsGroup A: AIH patients
Group B: Control patients
Trial outcomes
Primary outcomes
1
Identification of new immune, cellular and molecular markers in patients who respond and not respond to treatment
Comparative studies of clinical, biological, genetic (HLA typing) parameters and result from omics analysis of patients groups classified according to their response to treatment and disease progression
Time frame
2 yearsSecondary outcomes
1
Understanding the molecular mechanisms of treatment efficacy and failure
Combination of immunological, histological and therapeutic analysis
Time frame
2 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Nantes University Hospital
Lead sponsor
Direction Générale de l'Offre de Soins
Collaborator
Institut National de la Santé Et de la Recherche Médicale, France
Collaborator
National Cancer Institute, France
Collaborator
Association Française pour l'Etude du Foie (AFEF)
Collaborator
ALBI
Collaborator
FILFOIE
Collaborator
GIRCIGO
Collaborator
CR2TI-U1064
Collaborator
HEPATIM-GO network
Collaborator
CIC IMAD
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: