This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.
Able to understand and willing to sign a written informed consent document.
Age ≥ 18 and ≤ 75 years.
Male or female.
Karnofsky physical status (KPS): ≥ 80
Distant metastatic disease
Have a history of other cancers or coinstantaneous second primary tumor
Previous treatment for the primary tumor, including radiotherapy, surgery except biopsy operation, chemotherapy, immunotherapy and biological targeted therapy.
Patients who have participated in other clinical trials within 1 month before the test.
Eye & ENT Hospital of Fudan University
Lead sponsor
Shandong Provincial Hospital
Collaborator
Harbin Medical University Third Affiliated Hospital
Collaborator