About this trial
The primary aim of this randomized cross-over intervention study is to investigate the effect of four weeks of intermittent carbohydrate restriction (alternating between two days of normal dietary intake and two days of carbohydrate restriction to 70-90 grams) on 24-hour average sensor glucose in individuals with type 2 diabetes compared with a four-week control period with normal dietary intake.
Eligibility criteria
Qualifiers
Men or women
35-75 years old
BMI >27 kg/m2
Known type 2 diabetes in stable glucose lowering therapy (for three months) or with HbA1c >48 mmol/mol if no glucose lowering therapy
Disqualifiers
Anemia (hemoglobin <8 mmol/L for men and <7 mmol/L for women)
TSH outside reference range
Treatment with insulin, sulfonylurea, or SGLT2-inhibitors
Treatment with systemic corticosteroids
Trial design
Treatments tested in this trial
- Dietary macronutrient composition
Treatment groups
Sponsors and collaborators
Hvidovre University Hospital
Lead sponsor
University of Copenhagen
Collaborator
Danish Research Centre for Magnetic Resonance
Collaborator