Health Trials

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

ConditionsOncologyBreast CancerProstate CancerGynecologic CancerBrain TumorBrain CancerGynecologic TumorProstate TumorProstate NeoplasmBreast TumorRadiation ToxicityQuality of LifeRectal CancerRectal TumorRectal NeoplasmsLung CancerLung TumorLung NeoplasmEsophageal CancerEsophagus CancerEsophageal TumorEsophageal NeoplasmEsophagus TumorEsophagus NeoplasmPancreatic CancerPancreatic TumorPancreatic NeoplasmsHead and Neck CancerHead and Neck NeoplasmsHead and Neck TumorTumorNeoplasmsBladder CancerBladder NeoplasmLiver CancerLiver NeoplasmsLiver MetastasesOligometastases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUMC Utrecht

About this trial

The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose to improve patients' survival, local, and regional tumor control and quality of life.

Eligibility criteria

Qualifiers

Patient is to undergo or has completed imaging or treatment procedures on an MR-Linac;

Patient provides written, informed consent;

Patient is 18 years old or older.

Disqualifiers

MRI exclusion criteria, including

MRI contraindications as per usual clinical care, such as (possible) pregnancy; claustrophobia and metal or electronic implants not compatible with MRI.

Trial design

Treatments tested in this trial

  • Radiation therapy

Treatment groups

8,000 Participants
are divided into 13 treatment groups

13

Treatment groups

See each treatment group below.

Sponsors and collaborators

UMC Utrecht

Lead sponsor

The Netherlands Cancer Institute

Collaborator

Sunnybrook Health Sciences Centre

Collaborator

M.D. Anderson Cancer Center

Collaborator

The Christie NHS Foundation Trust

Collaborator

Royal Marsden NHS Foundation Trust

Collaborator

Medical College of Wisconsin

Collaborator

Elekta Limited

Collaborator

Odense University Hospital

Collaborator

Radboud University Medical Center

Collaborator

Radiotherapiegroep

Collaborator

Jules Bordet Institute

Collaborator

University Hospital Tuebingen

Collaborator

Radiotherapeutic Institute Friesland

Collaborator

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Collaborator

IRCCS Sacro Cuore Don Calabria di Negrar

Collaborator

Austin Health

Collaborator

Princess Margaret Hospital, Canada

Collaborator

Università degli Studi di Brescia

Collaborator

Source ClinicalTrials.gov