The Motor Activity - Subjective Energy (MASE) Project

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Bern

About this trial

This approach utilizes accelerometry to measure NEA and electronic diaries for real-time psychological assessments, overcoming limitations of traditional methods such as retrospective bias and low ecological validity. Brief episodes of physical activity in daily life, which are distinctly different from structured exercise sessions, are generally linked to improved affective well-being. Notably, feelings of energy are particularly associated with incidental, unstructured, and non-exercise activities. Clinically, psychomotor retardation and diminished mood are key diagnostic features of MDD, with evidence suggesting that lower motor activity differentiates MDD patients from controls and that increased activity correlates with treatment response. In this context, the MASE project aims to design personalized BA interventions that focus on increasing NEA and, in turn, enhancing subjective energy levels to reduce depressive symptoms and prevent relapse.

Eligibility criteria

Qualifiers

Sufficient knowledge of the German language

Written informed consent.

Score > 15 on the Montgomery Asberg Depression rating scale (MADRS) for MDD group.

Remission within the past year and exhibit a MADRS score < 10 for at least one month for rMDD group

Disqualifiers

Pregnancy at baseline

Claustrophobia

Pacemaker

Artificial heart valves

Trial design

Treatments tested in this trial

  • Non-exercise activity

Treatment groups

180 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University of Bern

Lead sponsor

University of Salzburg

Collaborator

University of Wuerzburg

Collaborator

University of Mannheim

Collaborator

University of Ostrava

Collaborator

University of Deusto

Collaborator