The Outreach and Prevention at ALcohol Venues in East Africa Study (OPAL-East Africa- Aim 2) (OPAL-Aim 2)

ConditionHIV/AIDS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, San Francisco

About this trial

This study will evaluate the effect of a brief alcohol counseling intervention on PrEP and PEP adherence among adults with heavy alcohol use at high risk for HIV, while gaining insights into the facilitators, barriers, and cost-effectiveness of this approach.

Eligibility criteria

Qualifiers

Adult (≥18 years)

HIV-uninfected (by rapid HIV antibody test)

AUDIT-C score of >=4 for men and >=3 for women

Attending a clinical visit for initiation of biomedical HIV prevention with oral or injectable PrEP or oral PEP (or the dapivirine vaginal ring, if available)

Disqualifiers

Ineligible for PrEP based on MoH guidelines

Intention to move away from the study community in the coming year

Gross inebriation or inability to provide informed consent

Trial design

Treatments tested in this trial

  • Healthy Living Intervention (HLI)
  • Standard of Care

Treatment groups

400 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of California, San Francisco

Lead sponsor

University of California, Berkeley

Collaborator

Makerere University

Collaborator

Infectious Diseases Research Collaboration, Uganda

Collaborator

Kenya Medical Research Institute

Collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborator