The Pattern of Dry Eye Disease After Cataract Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-90
SponsorLithuanian University of Health Sciences
About this trial
This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.
Eligibility criteria
Qualifiers
Cataract patients from 50 to 90 years old who underwent uncomplicated phacoemulsification performed by one (and same) experienced surgeon.
Patients with no underlying ocular surface diseases (keratitis, keratoconjunctivitis and others).
Patients who previously did not undergo any ophthalmic surgery.
Disqualifiers
Patient expressed his wish to not participate in the study or discontinue it when already enrolled.
Severe dry eye disease diagnosed with OSDI/DEQ-5 and at least one of the following tests: TBUT less than 10 seconds, tear osmolarity higher than 308 mOsm/l or positive corneal staining.
Glaucoma.
Diabetes mellitus.
Trial design
Treatments tested in this trial
- Artificial tears (sodium hyaluronate 0.2%)
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Lithuanian University of Health Sciences
Lead sponsor
Santen Oy
Collaborator
Source ClinicalTrials.gov