The Physiology of Human Brown Adipose Tissue

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorBeth Israel Deaconess Medical Center

About this trial

Brown fat is a type of fat, found in both children and adults, which can produce heat and regulate the body's metabolism and energy use. White fat is the more common type of fat which is used to store extra calories. Understanding more about differences between brown and white fat may allow us to develop new approaches to improve the body's metabolism.

Eligibility criteria

Qualifiers

None

Disqualifiers

Body mass index (BMI) greater than or equal to 40 kg/m2

History of any local or systemic infectious disease with fever or requiring antibiotic within four weeks of drug administration;

Diabetes, either previously diagnosed or hemoglobin A1c greater than or equal to 6.5%

Use of oral or parenteral corticosteroids (epidural permitted) or other medication known to cause insulin resistance in the previous 6 weeks.

Trial design

Treatments tested in this trial

  • Fat biopsy
  • Blood sampling
  • Blood sample for DNA analysis

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

Beth Israel Deaconess Medical Center

Lead sponsor

Joslin Diabetes Center

Collaborator

Chan Zuckerberg Initiative

Collaborator