The Recurrence Gene Profiles of Adjuvant Osimertinib Therapy in Resected Non-Small-Cell Lung Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorHunan Province Tumor Hospital

About this trial

This study was a multicenter, real-world observational study aimed at characterizing the genomic landscape of recurrence in patients with EGFR-sensitizing mutation-positive early-stage (clinical stage IB-IIIA) non-small cell lung cancer who received adjuvant osimertinib after surgery.

Eligibility criteria

Qualifiers

Informed consent signed;

Age ≥ 18 years;

Histologically confirmed diagnosis of non-squamous non-small cell lung cancer;

Patients with stage IB-IIIA (TNM 8#) NSCLC undergo confirmed radical R0 resection;

Disqualifiers

Patients with stage I-III NSCLC whose surgical resection cannot be confirmed;

Received adjuvant therapy other than that specified in the ADAURA study;

No NGS test report at recurrence;

History of other malignant tumors within 2 years;

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

60 Participants
are grouped into 2 trial groups

Sponsors and collaborators