The Relationship Between Diet, Cognition, Stress, and the Gut Microbiota

ConditionHealthy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-50
SponsorUniversity College Cork

About this trial

This study aims to investigate the relationship between diet and the microbiota-gut-brain axis.

Eligibility criteria

Qualifiers

Be able to give written informed consent.

Be between 18 and 50 years of age.

Have a body mass index (BMI) between 18.5-29.9 Kg/m2.

Be in generally good health as determined by the investigator.

Disqualifiers

Are less than 18 and greater than 50 years of age.

Have a BMI below 18.5 or above 29.9 Kg/m2.

Have a significant acute or chronic coexisting illness [cardiovascular, gastrointestinal (GI) [to include functional GI disorders, inflammatory bowel disease, coeliac disease, lactose intolerance, food allergies], immunological, psychiatric [to include formal or as determined by MINI Psychiatric interview, diagnosis of current major depression, anxiety disorder, bipolar spectrum disorder, schizophrenia, other DSM-IV Axis I disorder], neurodevelopmental disorders, immunological, metabolic disorders [to include type I or II diabetes], or any condition which contraindicates, in the investigators judgement, entry to the study.

Have a condition or taking a medication that the investigator believes would interfere with the objectives of the study, pose a safety risk, or confound the interpretation of the study results; all psychoactive medications [to include anxiolytics, antipsychotics, antidepressants, anticonvulsants, centrally acting corticosteroids, and opioid pain relievers), laxatives, enemas, antibiotics, anti-coagulants, over-the counter non-steroidal anti-inflammatories (NSAIDS). Subjects should have a wash-out period of 4 weeks.

Trial design

Treatments tested in this trial

  • Dietary fibre

Treatment groups

350 Participants
are divided into 3 treatment groups

Sponsors and collaborators