Psoriasis is a common chronic and systemic immune-mediated disease, induced by a combination of genetic and environmental effects. The increasingly worrying question is the negative impact on patients' sleep, which has become an important comorbidity of psoriasis. To investigate the causal relationship between psoriasis and sleep status, a prospective cohort study will be conducted by separating moderate-to-severe psoriasis patients and healthy individuals into distinct cohorts in order to observe their sleep status.
In line with the diagnostic criteria of psoriasis
PASI>10 or BSA>10%
Understand and agree to participate in this study and sign the informed consent.
Those with serious mental diseases, such as depression, anxiety, etc;
PSQI>5 points;
Long term use of sedative and hypnotic drugs;
Patients with diabetes mellitus or severe heart, liver and kidney disease;