The Role of Anorectal Manometry in Pediatric Chronic Refractory Constipation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age4-18
SponsorAssiut University

About this trial

This research protocol outlines a two-year descriptive cross-sectional study to investigate the role of high-resolution anorectal manometry (HRAM) in children aged 4-18 years with chronic refractory constipation.The study plans to enroll 54 patients at Ain Shams University Specialized Hospital . The study aims to identify different patterns of anorectal dysfunction (like dyssynergic defecation or rectal hyposensitivity) using standardized international protocols. A key goal is to determine if these manometry findings can directly guide specific management strategies, such as biofeedback therapy for dyssynergia or botulinum toxin injections for anal hypertension. improving outcomes for children who do not respond to standard constipation therapies.

Eligibility criteria

Qualifiers

Children and adolescents aged from 4 to 18 years.

Participants who have chronic refractory constipation either functional or organic with or without fecal incontinence.

Cooperative patients.

Disqualifiers

Children aged less than 4 years old.

Uncooperative patients.

Children with anal fissures or any painful conditions that interfere with the procedure.

Trial design

Treatments tested in this trial

  • High resolution anorectal manometry using a multiuse water perfused catheter

Treatment groups

54 Participants
are divided into 1 treatment group

Sponsors and collaborators