The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMasaryk University
About this trial
The goal of this study is to clarify the role of the bacterium Cutibacterium acnes in the development of degenerative disc disease in patients with lumbar disc herniation who underwent microdiscectomy as part of their regular medical care.
Eligibility criteria
Qualifiers
minimum age of 18 years
MRI of the lumbosacral spine performed one month ± 2weeks before surgery showing a disc protrusion, herniation, or free nucleus pulposus sequestration
matching physical examination findings including positive straight leg raise test, dermatomal sensory deficits, myotome motor deficits, and diminished deep tendon reflexes.
Disqualifiers
antibiotics or corticosteroid use the month before surgery
ongoing bacterial or viral infection
immunocompromised patient
trauma
Trial design
Treatments tested in this trial
- Not listed
Trial groups
400 Participants
are grouped into 2 trial groupsSponsors and collaborators
Masaryk University
Lead sponsor
St. Anne's University Hospital Brno, Czech Republic
Collaborator
Source ClinicalTrials.gov