The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
ConditionHistamine
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-45
SponsorUniversity Ghent
About this trial
Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.
Eligibility criteria
Qualifiers
Male
18-45 years
Not to medium physically active
Disqualifiers
Smoking
Chronic disease
High blood pressure
Supplement or medication intake
Trial design
Treatments tested in this trial
- Placebo
- H1 blockade: Telfast: 180mg Fexofenadine
- Resistance training
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
University Ghent
Lead sponsor
Research Foundation Flanders
Collaborator
Source ClinicalTrials.gov