The Role of Intestinal Microbiota Dysbiosis in the Development of Spondyloarthritis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
The primary objective of this case-control study aims to explore the role of bacterium Ruminococcus gnavus (R. gnavus) with intestinal biopsy and faecal sampling in the initiation and the development of spondyloarthritis (SPA) in comparison with health control subjets (patients without chronic disease but have indication to digestive endoscopy).
Eligibility criteria
Qualifiers
Patients ⩾ 18 years;
Diagnosed as spondyloarthritis (SpA) according ASAS classification;
Affiliated to a social security scheme;
Have signed the written informed consent form.
Disqualifiers
Subjects unable to understand the proposed study and/or sign a informed consent form;
Pregnant women or breast feeding women;
Subjects under guardianship or curatorship;
Have taken antibiotic 1 month prior to inclusion;
Trial design
Treatments tested in this trial
- Biopsy
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov