The Role of TRP Channels in DPN
ConditionPhysiological Responses
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-45
SponsorUniversitaire Ziekenhuizen KU Leuven
About this trial
The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers. The vascular response will be characterized in terms of response over time, dose-response, inter-foot and inter-period reproducibility.
Eligibility criteria
Qualifiers
Subject is a white male or female ≥18 and ≤45 years of age
Subject is a non-smoker for at least 6 months prior to the start of the study
Subject has a body mass index (BMI) between 18-30 kg/m²
Subject is judged to be in good general health on the basis of medical history, physical examination and vital signs
Disqualifiers
Subject has a history of any illness or disorder which, in the investigator's opinion, might confound the results of the study
Subject has a history of significant severe (drug) allergies
Subject is a female who is pregnant, breast-feeding or intends to become pregnant, or is of child-bearing potential and is not using an adequate contraceptive method
Subject uses any prescription or non-prescription drugs on a regular basis which, in the investigator's opinion, might confound the results of the study
Trial design
Treatments tested in this trial
- Cinnamaldehyde
- Allyl isothiocyanate (AITC)
- Capsaicin
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov