About this trial
The goal of this clinical trial is to evaluate the effectiveness and cost-effectiveness of a digital mindfulness-based intervention in adults (aged 18-65) diagnosed with emotional disorders like depression or anxiety. The main questions it aims to answer are:
* Does adding a digital mindfulness intervention to usual care help people recover from emotional disorders faster and more sustainably over two years? * Is this combined approach more cost-effective than usual care alone? Researchers will compare the group receiving the digital mindfulness intervention plus their usual treatment to the group receiving only their usual treatment to see if the intervention leads to better long-term recovery and represents good value for money.
Participants in the intervention group will:
* Attend eight weekly 2-hour online group mindfulness sessions. * Use a WeChat mini-program for 49 days of guided mindfulness exercises and daily tasks. * Patients who have not achieved reliable recovery after group retraining voluntarily participate in individual UP\&MIED counseling. * Complete regular questionnaires and interviews over two years to track their progress.
All participants will continue to receive their usual medical care from their doctors throughout the study.
Eligibility criteria
Qualifiers
Age: 18-65 years.
Diagnosed with an emotional disorder by a outpatient psychiatrist, including depressive disorders, anxiety disorders (e.g., generalized anxiety disorder, panic disorder, agoraphobia, social anxiety disorder), obsessive-compulsive disorder, post-traumatic stress disorder, and eating disorders (e.g., anorexia nervosa, bulimia nervosa).
Symptom severity meeting the threshold: PHQ-9 score ≥10 or GAD-7 score ≥8.
Disqualifiers
Current diagnosis of psychotic disorders or bipolar disorder.
Current organic mental disorders, pervasive developmental disorders, severe cognitive impairment, or substance use disorders.
Current suicide risk (PHQ-9 item 9 score >2).
Antisocial personality disorder.
Trial design
Treatments tested in this trial
- Mindfulness Intervention for Emotional Distress
Treatment groups
Sponsors and collaborators
Peking University
Lead sponsor
WU'AN FIRST PEOPLE'S HOSPITAL
Collaborator
Xi'an Mental Health Center
Collaborator
The Second Hospital of Anhui Medical University
Collaborator
The Guangxi Zhuang Autonomous Region Brain Hospital
Collaborator
DONG GUAN SEVENTH PEOPLE'S HOSPITAL
Collaborator
Affiliated Mental Health Center of Kunming Medical University
Collaborator
People's Hospital of Zhengzhou University
Collaborator
The Affiliated Brain Hospital of Guangzhou Medical University
Collaborator
THE SIXTH AFFILIATED HOSPITAL OF GUANGDONG PHARMACEUTICAL UNIVERSITY
Collaborator
Xiamen Medical College Affiliated Xian Yue Hospital
Collaborator