The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
RA patients (ACR/EULAR2010 criteria)
Age >18-years
Disease duration >1-year
Active disease (DAS28 > 2.6units)
Prednisolone dose ≥ 7.5 mg/day
Antibiotic therapy 4-weeks prior to baseline
Persistent use of NSAID's
Inflammatory or irritable bowel disease
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Lead sponsor
Gulbenkian Institute for Molecular Medicine
Collaborator