About this trial
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource poor areas antibiotics are still prescribed at high rates due to pressures such as financial incentives, caregiver expectations, and diagnostic uncertainty. Informal healthcare providers often serve as first point of care for pediatric diarrhea patients in low- and middle- income countries (LMICs) and commonly prescribe antibiotics for pediatric diarrhea at high frequencies.
In this pilot before-after feasibility trial informally trained healthcare providers will use a mobile phone-based application (Accessible Diarrhea Etiology Prediction Tool, ADEPT) which will allow for the exploration of the acceptability, feasibility, and utility of the tool, as well as ADEPTs ability to decrease inappropriate antibiotic prescribing practices.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Village Doctor with antibiotic prescribing authority for children presenting with diarrheal illness
Practice in trial location subdistrict
Self-report treating a minimum of 5 pediatric diarrhea cases per week
Willing to participate in ADEPT training, use ADEPT in clinical practice with pediatric diarrhea patients, and to collect, via an electronic tool, data on patient characteristics and clinical management
Disqualifiers
None
Trial design
Single group
Treatments tested in this trial
Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
Diagnostic testThe ADEPT tool allows providers to input information about pediatric diarrhea patients and provides outputs related to dehydration management and potential treatment.
Treatment groups
Trial outcomes
Primary outcomes
Proportion of pediatric diarrhea encounters resulting in antibiotic prescription
By self-report, before vs after ADEPT implementation
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Daniel Leung
Lead sponsor
University of Utah
Sponsor institution
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator
International Centre for Diarrhoeal Disease Research, Bangladesh
Collaborator
This trial is not recruiting at the moment. You can still explore other options: