About this trial
Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography are associated with coagulation-related damages secondary to traumatic brain injury, and evaluate their influence on outcome among patients with head trauma. Based on above results, prediction models or risk scoring systems will be further developed and validated to predict coagulation-related damages secondary to traumatic brain injury.
Eligibility criteria
Qualifiers
Patients who are delivered to hospital within 24 hours after head trauma
Patients whose abbreviated injury score (AIS) for other body regions is 3 or less are considered to be isolated traumatic brain injury
Disqualifiers
Patients with existing prior neurological disease
Patients with known coagulation disorders
Patients on anticoagulants and medications known to affect coagulation function within 30 days before trauma
Patients receiving blood components prior to blood draw
Trial design
Treatments tested in this trial
- Not listed