Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSir Run Run Shaw Hospital

About this trial

This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy evaluation and prognostic prediction of the LVO patients with low NIHSS.

Eligibility criteria

Qualifiers

Aged 18 years or older

Acute ischemic stroke patients of NIHSS 0-5 with 24 hours after onset

Proximal intracranial artery occlusion on NCCT/CTA or MRI/MRA showing occlusion of the intracranial ICA, M1, or proximal M2 vessel

Baseline ASPECTS ≥6 or infarct Core Volume of < 70 on NCCT/DWI/CTP

Disqualifiers

Any sign of intracranial hemorrhage on baseline CT/MR;

Seizures at stroke onset

Baseline blood glucose of <2.78 mmol or >22.20 mmol, or platelet count < 100,000/uL or serum creatinine levels > 3.0 mg/dL

Participation in any investigational study in the previous 30 days

Trial design

Treatments tested in this trial

  • Immediate endovascular therapy

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators