About this trial
This clinical trial aims to evaluate dentin bridge formation over the pulp following selective caries removal in permanent teeth with deep carious lesions (ICDAS scores 5-6). A total of 66 patients will be enrolled and randomly allocated to receive either a bioactive restorative system (bioactive universal adhesive combined with a bioactive bulk-fill resin composite) or a conventional non-bioactive restorative system. Clinical assessments, including pulp sensibility testing and patient-reported pain evaluation, together with three-dimensional radiographic analysis using cone beam computed tomography, will be conducted to assess the thickness and quality of reparative dentin bridge formation. Outcomes will be evaluated at baseline and during follow-up periods extending up to 24 months to compare the effectiveness of both restorative approaches in preserving pulp sensibility and promoting dentin-pulp complex repair.
Eligibility criteria
Qualifiers
Adult patients (age: 18-40 years) of both genders.
Good oral hygiene.
Willing to sign the informed consent.
Cooperative patients who accept the follow-up period.
Disqualifiers
Allergy to any of the restorative materials.
Patients undergoing orthodontic treatment with fixed appliances.
Pregnant women.
Patients with debilitating systemic diseases.
Trial design
Treatments tested in this trial
- Experimental - Bioactive Restorative System
- Active Comparator -Conventional Restorative System